protopathic

adjective

Sensing pain, pressure, heat, or cold in a nonspecific manner, usually without localizing the stimulus. Used especially of certain sensory nerves.

Pertaining to the original lesion of a disease; primary.

adjective

Relating to a sensory nerve that detects the presence of a stimulus without determining its location.

adjective

Relating to first symptoms of a disease, as in the sense of protopathic bias